Abiraterone Acetate*
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API Product :
Abiraterone Acetate*
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CEP :
-
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WCC :
?
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Therapeutic Use :
Psycholeptics; Cytostatic Hormone Therapy
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Originator :
Johnson and Johnson
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CAS No. :
154229-18-2
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Trade Name. :
Zytiga
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Molecular Weight :
391.555 g/mol
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Molecular Formula :
C26H33NO2
Application
Abiraterone acetate is indicated for use in combination with prednisone for the treatment of men with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel.
General Description
Abiraterone, developmental code name CB-7598, also known as 17-(3-pyridyl)androsta-5,16-dien-3-ol, is a synthetic, steroidal CYP17A1 inhibitor. It is the active metabolite of abiraterone acetate, an ester and prodrug of abiraterone. A metabolite of abiraterone has been found to act as an agonist of the androgen receptor, and may antagonize the clinical effectiveness of abiraterone acetate.