Product Name : Ambroxol 60% Pellets
Dosage Form : Capsules
Dose : 75mg
Therapeutic Category : Respiratory Products
Reference Product : Ambrox
API : DMF; Dossier — CTD : Available
Trade Name : Ambrox®
Originator : Boehringer Ingelheim; Teijin Pharma
Ambroxol is a mucolytic agent which reduces the thickness of the sputum. It is used to treat conditions with abnormal mucus secretion, allowing the patient to breathe freely and deeply.
Ambroxol is a drug that breaks up phlegm, used in the treatment of respiratory diseases associated with viscid or excessive mucus. Recently, a hypothesis suggested that it may have a potential role in treatment of Paget's disease of bone, Parkinsonism, and other common diseases of aging-associated diseases involving dysfunction of autophagy. It is the active ingredient of Mucosolvan, Mucobrox, Mucol, Lasolvan, Mucoangin, Surbronc, Ambolar, and Lysopain. The substance acts on mucus membranes, restoring the physiological clearance mechanisms of the respiratory tract (which play an important role in the body’s natural defence mechanisms) through several mechanisms, including breaking up phlegm, stimulating mucus production, and stimulating synthesis and release of surfactant by type II pneumocytes. Surfactant acts as an anti-glue factor by reducing the adhesion of mucus to the bronchial wall, in improving its transport and in providing protection against infection and irritating agents. Ambroxol is often administered as an active ingredient in cough syrup.