API Product   :    Tadalafil*
CEP   :    ¤
WCC   :    ?
Therapeutic Use    :    Urologicals; Other cardiovascular products
Urologicals; Other cardiovascular products
Originator   :    Eli Lilly
CAS No.    :    171596-29-5
Trade Name.   :    CIALIS
Molecular Weight   :    389.404 g/mol
Molecular Formula   :    C22H19N3O4
Tadalafil relaxes muscles of the blood vessels and increases blood flow to particular areas of the body. Tadalafil under the name of Cialis is used to treat erectile dysfunction (impotence) and symptoms of benign prostatic hypertrophy (enlarged prostate).
Tadalafil (INN) is a PDE5 inhibitor marketed in pill form for treating erectile dysfunction (ED) under the names Cialis /si?æl?s/ see-AL-iss, Adcirca /æd?s??rk?/ ad-SUR-k?, and Tadacip for the treatment of pulmonary arterial hypertension. In October 2011 the U.S. Food and Drug Administration (FDA) approved Cialis for treating the signs and symptoms of benign prostatic hyperplasia (BPH) as well as a combination of BPH and erectile dysfunction when the conditions coincide. It initially was developed by the biotechnology company ICOS, and then again developed and marketed worldwide by Lilly ICOS, LLC, the joint venture of ICOS Corporation and Eli Lilly and Company. Cialis tablets, in 2.5 mg, 5 mg, 10 mg, and 20 mg doses, are yellow, film-coated, and almond-shaped. The approved dose for pulmonary arterial hypertension is 40 mg (two 20 mg tablets) once per day (OD).