API Product   :    Cabazitaxel*
CEP   :    -
WCC   :    ?
Therapeutic Use    :    Antineoplastics
Originator   :    SANOFI AVENTIS PHR
CAS No.    :    183133-96-2
Trade Name.   :    JEVTANA KIT
Molecular Weight   :    835.93 g/mol
Molecular Formula   :    C45H57NO14
Cabazitaxel (Jevtana) is a microtubule inhibitor indicated in combination with prednisone for treatment of patients with hormone-refractory metastatic prostate cancer previously treated with a docetaxel- containing treatment regimen.
Cabazitaxel (previously XRP-6258, trade name Jevtana) is a semi-synthetic derivative of a natural taxoid.[1] It was developed by Sanofi-Aventis and was approved by the U.S. FDA for the treatment of hormone-refractory prostate cancer on June 17, 2010. It is a microtubule inhibitor, and the fourth taxane to be approved as a cancer therapy.