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Active Pharmaceutical Ingredients (APIs)
  • Cabazitaxel*

    • API Product   :   

      Cabazitaxel*

    • CEP   :   

      -

    • WCC   :   

      ?

    • Therapeutic Use    :   

      Antineoplastics

    • Originator   :   

      SANOFI AVENTIS PHR

    • CAS No.    :   

      183133-96-2

    • Trade Name.   :   

      JEVTANA KIT

    • Molecular Weight   :   

      835.93 g/mol

    • Molecular Formula   :   

      C45H57NO14

    Application

    Cabazitaxel (Jevtana) is a microtubule inhibitor indicated in combination with prednisone for treatment of patients with hormone-refractory metastatic prostate cancer previously treated with a docetaxel- containing treatment regimen.

    General Description

    Cabazitaxel (previously XRP-6258, trade name Jevtana) is a semi-synthetic derivative of a natural taxoid.[1] It was developed by Sanofi-Aventis and was approved by the U.S. FDA for the treatment of hormone-refractory prostate cancer on June 17, 2010. It is a microtubule inhibitor, and the fourth taxane to be approved as a cancer therapy.

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