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Active Pharmaceutical Ingredients (APIs)
  • Donepezil HCI

    • API Product   :   

      Donepezil HCI

    • CEP   :   

      -

    • WCC   :   

      ?

    • Therapeutic Use    :   

      Psychoanaleptics Excluding Anti-Obesity Preparations; Other CNS Drugs

    • Originator   :   

      Eisai

    • CAS No.    :   

      120014-06-4

    • Trade Name.   :   

      ARICEPT

    • Molecular Weight   :   

      379.50 g/ mol

    • Molecular Formula   :   

      C24H29NO3

    Application

    Donepezil is used to treat confusion (dementia) related to Alzheimer's disease. It does not cure Alzheimer's disease, but it may improve memory, awareness, and the ability to function. This medication is an enzyme blocker that works by restoring the balance of natural substances (neurotransmitters) in the brain.

    General Description

    Donepezil, marketed under the trade name Aricept, is a medication used in the palliative treatment of Alzheimer's disease.[1][2] Donepezil is used to improve cognition and behavior of people with Alzheimer's, but does not slow the progression of or cure the disease.[3] Common side effects include loss of appetite, gastrointestinal upset, diarrhea, difficulty sleeping, vomiting, or muscle cramping.[4] It was developed by Eisai and Pfizer and is sold as a generic by multiple suppliers. Donepezil acts as a centrally acting reversible acetylcholinesterase inhibitor.

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