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Active Pharmaceutical Ingredients (APIs)
  • Gefitinib

    • API Product   :   

      Gefitinib

    • CEP   :   

      -

    • WCC   :   

      ?

    • Therapeutic Use    :   

      Antineoplastics

    • Originator   :   

      ASTRAZENECA

    • CAS No.    :   

      184475-35-2

    • Trade Name.   :   

      IRESSA

    • Molecular Weight   :   

      446.902 g/mol

    • Molecular Formula   :   

      C22H24ClFN4O3

    Application

    Gefitinib is used to treat lung cancer. It works by slowing or stopping the growth of cancer cells. Gefitinib blocks a certain protein (an enzyme called tyrosine kinase).

    General Description

    Gefitinib (ZD1839) ( trade name Iressa)[1] is a drug used for certain breast, lung and other cancers. Gefitinib is an EGFR inhibitor, like erlotinib, which interrupts signaling through the epidermal growth factor receptor (EGFR) in target cells. Therefore, it is only effective in cancers with mutated and overactive EGFR. It is marketed by AstraZeneca and Teva.

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