Product Name   :    Nicardipine 20% SR Pellets
Dosage Form   :    Capsules
Dose   :    30mg
Therapeutic Category   :    Cardiovascular
Reference Product   :    Cardene SR
API : DMF; Dossier — CTD   :    Available
Trade Name   :    Cardene SR®
Originator   :    GlaxoSmithKline
Nicardipine is used with or without other medications to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Nicardipine is called a calcium channel blocker.
"Nicardipine (Cardene) is a medication used to treat high blood pressure and angina. It belongs to the dihydropyridine class of calcium channel blockers. It is also used for Raynaud's phenomenon. It is available in by mouth and intravenous formulations. Its mechanism of action and clinical effects closely resemble those of nifedipine and the other dihydropyridines (amlodipine, felodipine), except that nicardipine is more selective for cerebral and coronary blood vessels. Nicardipine also has a longer half-life than nifedipine. Nicardipine was approved by the FDA in December 1988. The patent for both Cardene and Cardene SR expired in October 1995. It has been used in percutaneous coronary intervention."