API Product   :    Metformin HCl
CEP   :    ¤
WCC   :    ?
Therapeutic Use    :    Cholagogues and hepatic protectors; All Other Therapeutic Products; Drugs used in diabetes; Other dermatological preparations
Originator   :    Bristol-Myers Squibb; Merck & Co; Zuellig
CAS No.    :    657-24-9
Trade Name.   :    GLUCOPHAGE
Molecular Weight   :    129.16364 g/mol
Molecular Formula   :    C4H11N5
Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problem.
Metformin, marketed under the trade name Glucophage among others, is the first-line medication for the treatment of type 2 diabetes,[5][6] particularly in people who are overweight.[7] It is also used in the treatment of polycystic ovary syndrome (PCOS).[5] Limited evidence suggests metformin may prevent the cardiovascular disease and cancer complications of diabetes.[8][9] It is not associated with weight gain.[9] It is taken by mouth.[5] Metformin is generally well tolerated.[10] Common side effects include diarrhea, nausea and abdominal pain.[5] It has a low risk of causing low blood sugar.[5] High blood lactic acid level is a concern if the medication is prescribed inappropriately and in overly large doses.[11] It should not be used in those with significant liver disease or kidney problems.[5] While no clear harm comes from use during pregnancy, insulin is generally preferred for gestational diabetes.[5][12] Metformin is in the biguanide class.[5] It works by decreasing glucose production by the liver and increasing the insulin sensitivity of body tissues.