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  • Metformin HCI 90.0% DC Granules

    • Product Name   :   

      Metformin HCI 90.0% DC Granules

    • Dosage Form   :   

      Tablets

    • Dose   :   

      500mg

    • Reference Product   :   

      USV Europe

    • API : DMF; Dossier — CTD   :   

      Available

    • Originator   :   

      Bayer 

    Application

    Treatment of type 2 diabetes mellitus, particularly in over weight patients, when dietary management and exercise alone does not result in adequate glycemic control. In adults, Metformin film-coated tablets may be used as monotherapy or in combination with other oral anti-diabetic agents or with insulin.

    General Description

    Metformin, marketed under the trade name Glucophage among others, is the first-line medication for the treatment of type 2 diabetes,[5][6] particularly in people who are overweight.[7] It is also used in the treatment of polycystic ovary syndrome (PCOS).[5] Limited evidence suggests metformin may prevent the cardiovascular disease and cancer complications of diabetes.[8][9] It is not associated with weight gain.[9] It is taken by mouth.[5] Metformin is generally well tolerated.[10] Common side effects include diarrhea, nausea and abdominal pain.[5] It has a low risk of causing low blood sugar.[5] High blood lactic acid level is a concern if the medication is prescribed inappropriately and in overly large doses.[11] It should not be used in those with significant liver disease or kidney problems.[5] While no clear harm comes from use during pregnancy, insulin is generally preferred for gestational diabetes.[5][12] Metformin is in the biguanide class.[5] It works by decreasing glucose production by the liver and increasing the insulin sensitivity of body tissues.

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